Absorción de nutrientes en corderos alimentados con dietas con diferentes cantidades de fósforo / Nutrient absorption in lambs fed diets containing different amounts of phosphorus

Objective. Evaluate the effect of increasing P intake on nutrient digestibility, and compare the true and apparent absorption coefficients of P and Ca in lambs. Materials and methods. Twenty-four Santa Ines sheep, with an average weight of 33.6 ± 1.6 kg, were distributed into four treatments (0, 2, 4 and 6 g/day of supplementary P) with forage: concentrate ratio of 70:30. The study of apparent nutrient digestibility was conducted during the first week, using the total feces collection method. During the second week, after injection of 7.4 MBq of 32P and 7.7 MBq of 45Ca, apparent (AAC) and true (TAC) absorption coefficients of P and Ca were determined. The lambs were kept in metabolic cages. Results. The increase in P intake did not affect (p>0.05) dry matter, crude protein, NDF or ADF digestibility, but the TAC of P and Ca and mineral matter digestibility decreased. The AAC was not affected (p=0.10). A cubic relationship was observed between P intake and TAC (TAC=2.16–1.95X+0.55X2-0.04X3; R2=0.38) and linear relationship with the TAC of Ca (TAC=0.559–0.03X; R2=0.26). TAC and AAC values were different (p<0.001). Conclusions. The increase in P intake doesn’t impact organic matter digestibility, but does affect P and Ca absorption. Apparent digestibility is not a reliable parameter to determine the efficiency of P and Ca absorption.

Objetivo. Evaluar el efecto del incremento en la ingestión de P sobre la digestibilidad de los nutrientes, y comparar los coeficientes de digestibilidad real y aparente de Ca y P en ovinos. Materiales y métodos. Veinticuatro ovinos de la raza Santa Inés, con 33.6±1.6 kg de peso, fueron asignados a cuatro tratamientos (0, 2, 4 y 6 g/día de P suplementario) con relación forraje:concentrado de 70:30. El estudio de digestibilidad aparente de los nutrientes se realizó la primera semana usando el método de colecta total de heces. La segunda semana, luego de inyectar 7.4 MBq de 32P y 7.7 MBq de 45Ca, se realizó el estudio de absorción real (CAV) y aparente (AAC), en jaulas de estudio de metabolismo. Resultados. El incremento en la ingestión de P no afectó (p>0.05) la digestibilidad aparente de la materia seca, proteína bruta, FDN o FDA. El CAV de Ca y de P y la digestibilidad de la materia mineral presentaron una reducción. EL AAC no fue afectado (p=0.10). La ecuación CAV=2.16–1.95X+0.55X2-0.04X3 (R2 = 0.38) explicó la relación entre el CAV de P y el incremento en su ingestión, y la ecuación TAC=0.559 – 0.03X (R2=0.26), la relación entre el CAV de Ca y la ingestión de P. Los valores de AAC y CAV difirieron entre sí (p<0.001). Conclusiones. La ingestión de P no afectó la digestibilidad de la fracción orgánica del alimento, pero sí la absorción de P y Ca. El coeficiente de absorción aparente no fue un parámetro confiable para determinar la eficiencia de absorción de P y Ca.

relation between serum leptin and blood lipids in type 2 diabetic patients with ischemic heart disease

Background: the occurrence of ischemic heart disease in type 2 diabetic patients is very common and the cause is still not clear. Serum leptin had been accused to be the missing link between diabetes and coronary heart disease, but the mechanism is still not known. Serum lipids may contribute in this mechanism

Objective: This study has been performed to seek the possible relationship between serum leptin concentration and blood lipid concentration in diabetic patients with ischemic heart disease

Material and methods: The study included sixty subjects from the Internal Medicine Department inpatients of the Medical Research Institute Hospital who were previously admitted and diagnosed as group I: Type 2 diabetes with stable angina [15 patients], group II: Type 2 DM with unstable angina, group III: Type 2 DM with myocardial infarction and group IV: was 15 patients chosen as control group. All patients and controls were subjected to complete clinical and endocrinological examination. All patients and controls were subjected to estimation of fasting and post prandial blood glucose, high density lipoprotein cholesterol [HDL-ch], low density lipoprotein cholesterol [LDL-ch], total cholesterol [TC], and triacylglycerol [T G]. All patients and controls have been subjected to estimation of tasting serum leptin level

Results: No statistically significant correlation has been found between serum leptin and both fasting and post prandial blood glucose in all patients groups but when blood lipids were added, the correlation becomes positive. A statistically significant positive correlation has been found between [FBG, PPBG] and LDL-ch, TC, TG in all patients groups, whereas the correlation with HDL-ch was negative. A statistically signiticant positive correlation has been found between serum leptin and LDL-ch, TC and T6. The correlation was negative with HDL-ch

Conclusion: Increased levels of leptin together with decreased HDL-ch and increased TC, TG and LDL-ch are associated with unstable angina and acute mayocardial infarction. These findings support the theory that leptin levels should be monitored amongst other markers of cardiovascular risk

Usefulness of radiology and MRI in caudal regression syndrome

We report three patients with sacral and coccygeal agenesis based on observations of painful haematuria, urinary tract infection, and urine incontinence. All patients were examined by conventional radiology [urography and micturating urethrography] and imaging such as ultrasound and MRI. Neuropathic urinary bladder and pronounced reflux to the kidneys were observed. MRI of spine revealed conus medullaris located high [Th 11 and Th 12] and different from the expectations with respect to the patients' age. Neither tether cord nor intrathecal tumours were observed in our patients. In one patient, deformed and bulky cauda equina was described and in another the cauda equina was small and atrophic. In all patients, absence of a part of sacrum and coccyx and nerve roots innervating urinary bladder and sphincters were observed. MRI revealed good anatomical and pathological check up of kidneys and urinary tracts in the children suffering from chronic urosepsis